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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be1e34faaf3d3013c614a865bbece23463a0fdd79ed53921db7c8b05d28f328d' 
  AND token = 'UeAk05UpkF6ZEe4iW6VBXcvdqs6lrVLVyGPQqrgSRso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}