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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29cbf1a210c1315b320db5c36d4b18974b9b6a859fe48971c3cfef98f83d1570' 
  AND token = 'FiyRPpXcsJeOJtsNE+7eOjyUe4sAWlcgiUswqK4GEws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}