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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9c7a0959984f521aab82fccec71afb237e577b26ee4f285ec0ca3925e860a9f' 
  AND token = 'myl9aT2SVo934IMbCDc4N9tcpnm0qtlkBNgL3LvuXUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}