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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05df8348e39a9d13d373313b75198a40dcf7e4b74cdd0868b1b1ec872428355d' 
  AND token = 'EDbpPot2eoSB/zY+3Ai18Ccd+s4PlqppC/9cEVc2+cw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}