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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc5843bf4c9ca77a82d21974287bc8a375fd49cce54a8224c3b0a0374c59e31e' 
  AND token = 'CDsspzc6DRM06ByKu0yxQENuD3xF1EW0kFkM+2ZhsoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}