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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ccb29d3f70981d7a6e16d6eb3bc9f498b712d094330ee64be8ca8e2230e8b00' 
  AND token = 'P2P+H3lHOcwc1EXPoL4LR1nn5o4ifKSI7ZyzRyqlKxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}