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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c8eaaff6b2a4cc06256b21ea14d674ae46d84590b3d1e50483eb114bfa33e8b' 
  AND token = 'YW+mC/lWq42AiPzbtL95b0pFu9AtxYzQ3VsGcH3hdGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}