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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db3e890c5ca6eaf8a32ba4715a6b14b1a2bb2937636214d481bc0755633207bd' 
  AND token = 'gyCDyjePIgf9rahNfS1LLBaTnzOFfNPksDhIIP6XYBU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}