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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f26aa276211ebc06422a96f01942c89f075c76d3fbdbbffd0c24cef1a760efd' 
  AND token = 'islz8VP1GFtZIU3JSDJHnMwTPD/gbbtckeJ3jAZ3eZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}