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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45d4cc755afdc6a2bb7d23e5a320a79e8a38e7829ef0551533a52abd01784619' 
  AND token = 'RaElO801XT6+ZgaWaG+X1BGZf9I8PQlp5zq0gLuSrgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}