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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8e0254367d8a0de894ead8587e367690636ba37fb14e9892dd4a04bcdbc5773' 
  AND token = 'KUv74sL+KOtJziRT3nqT8xMJtedCTZQ1oTkekTuPiUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}