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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5eca86c421499c96e5c12dc6760d4db2d5298a27645337bf10425366f0d7930' 
  AND token = 'MW//VW16z5k2wnw4IYNq1UPqZ28j9B21rFUFJZiJ0Ls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}