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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebb27ef59b4cf8426acdd69d399a1db20a5f7d15727a9aca2913f790ce6014b9' 
  AND token = 'ao/wmnZNLzRFi0E8DcnGUngaUohK/FtDSnfUuybVYiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}