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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '886973469026a1fec0facb4d7786609c72cb848adb6a9d18b31de743d38cfa47' 
  AND token = 'kNfKI2SR7kV4CNbhkSUguJQkMGpX2dKPDNZNwZsUyto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}