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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb9d812700d0757e78e57806405b874c552943c96ca728c0acffcbfc13d1b971' 
  AND token = 't4SdNJByEXqk5B5cRZvzhgS8t3rivDi3QuNMHnQ05T8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}