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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '895198e17deb7082d6cfa69a6ac7a95030972c4d6d790777207cb1832c1b2162' 
  AND token = 'yUynRKa9zndFuo2V+JbCbCbipFcv4z65TLzPCI/o9Uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}