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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65742b27016ae6a45eac7534cba02b0804ead2154a52b30c526ff8f1883bd31a' 
  AND token = 'ImhUb+d7c/FXDo5TuxijGiIUGIzDR10V8ZTCDxfTw8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}