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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '811d3b746ef9eefe121eeb7bfe3eebfc3dda239ca816ace4309f9c238ef95fa9' 
  AND token = 'GVpHM+79e3ehE8jQ133eL+Ejo7jSwBiHxNQ3q8UwE5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}