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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22408da0820d22e8cdd7ed6d9f4e92437c4d92bc4a174f92aafc221bf8b2b54b' 
  AND token = '9Fa3g6jEuuEnSf3tBG1LxuZD/oUXUFOdThAYHqqGJfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}