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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09191274a5d8748a75c892e966202cc2db7a8651bc44ff66ea12df087ca595f8' 
  AND token = 'z2EP+2LL7lovkFWwKyE0K2xhFgw/K4ShidFu3ip3TWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}