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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '898251ab0785ce49b2cf99cbc6c2b45761ea7e34d58343e743b204f86be4eb3b' 
  AND token = 'OfTXOWDX+5UyZq0kgq7OocdlN5IxDWL+sSpKREbVk5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}