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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd00e39a081d6e3f712043016b0b36d242d041cd93db20c903da19d1da0a97d8' 
  AND token = 's+Je5YGUKAa2ZDFvdf/q6RyYj3hYpJl0yFZtVKwzy/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}