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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e991d4429e83f1ecebb287d314bd0f03b4fe20a0ed5d60b8e018f379b695125' 
  AND token = 'ur8c7IopfS7g82WH6EkzGhe8MBp4Ici68O643EqNwAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}