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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61875e9f4d767a2ecef77005bbc1d4625235e4bbf61759caac58936b1c8b1951' 
  AND token = 'p0z7EfNIoLLN5dHQyiCrU+6PVjWUVEyj8fMXqaR5sPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}