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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c51cf1d5dc9800d6753223adb8e6602b0c2f6825dbad850a29f9dc6a500e70e' 
  AND token = 'GAY2Cw6GGN7pf3/DsqIZqmykbUwVAdO2l0Juky8VIxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}