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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b1f9b9d9100b31a718c68fa4bbc711c35d8d2bd79213f87128cb609ffe3f266' 
  AND token = 'R43AZjUejjhVwdAisV6+O41ZNuKcQLFHMYCoEzVZ8dk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}