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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54a69423e12a1bc77ef2929eed9db67ac5f4dafce6e7e6414d66fff5c3377f74' 
  AND token = 'PTVEhJoKA/DgZYd4wFHy1LFSsJffonojwlnDt6bgZJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}