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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ea46881776d3cd22cbd58c6a3bbdd90e941b59e4331059908b7e0d5053d5371' 
  AND token = 'cqosaRASJQfq8Ru1wT9LMzVhVjwd7ORAg9Wqc4qYlIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}