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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de6628019fab0564efec6b2695cd9fbfa2637032a2c4d4024c012201f6fa10e7' 
  AND token = 'iS81+VCzLz8W7xCTjG99PX+CVhrACVLIsWU24m9OiJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}