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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6f1b5a25cab643f4d9adab8826c89ab0cc143662b9d6eb7a891efaaee580dfc' 
  AND token = '6UccmHXGvdr1nIrdOoDOopCAh6ra0nOWm+raQsODeCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}