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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a149559d8c4bb59dcea7931edb306278012880de368848dd432bb0582a38b79' 
  AND token = 'rUw30fReDMTTOwnwdhTc45jiX4nCcAe/VI7s3AZ+pPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}