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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6059e3c09746d12c38baffff6ff4bf20c24afef57b57c36cc70257e2d9534802' 
  AND token = 'sxuRBeGDWl4KBHeQDRI7HHXoRkU1ovOg0o6L9UJpmHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}