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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8b6eb374c60d5097f66affdb50b4006eb1c778a82a9d95760a01d7bab3721b0' 
  AND token = 'Dml/osQe1WzW7/Fg1nFb2XDrEF4WiwXWTtGa/AYdbTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}