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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '509fe1ed2962067962f813377128d7b70fe67bfd899be0e7cdbf6e3236fc1a63' 
  AND token = '7Dzd1jjbm+Re3NElifM4I2PQaPUgXudnalQl2xpz8tM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}