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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e1efabf751fa2038019329e863ff9d4f795c9b3a8c45caa20161779bb3ed046' 
  AND token = 'rxW/OXr+d8beyTRVhrxiSkdPQC+KbbK4FsHUK3IKIqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}