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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e157824bb1b22ed9357f954522d45dd30c287ab0ece7389d1ed57f139ddafc2c' 
  AND token = 'QGgplbUI/f9FJCC0n/BpO++3ekpBmzXiigAO/IOUa/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}