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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de9788dd3ec9b73d016ad48152588d4e33b3262342d7c381a810ec1295b6a851' 
  AND token = 'JbX2t3NMuMSW3cDjc24OSgTUUlu18VH2CQyHnGGexrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}