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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d415da3d7e3881bed32a55429c438bb9bc485ddef6804c5e49e59fd9e503f80' 
  AND token = 'C0f5Eyu+RDFL17EiSLaIEMJUbhjnvBkwdKSIzreDJ84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}