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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bffe91e433ef4d074f62fc9d11f1c4cfd3629deb60d53f53a2a77043174675c4' 
  AND token = 'o4IgoIaoLxDhkNUgPmb8cU7zqJBEEUb3s7I/2N1EDZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}