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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8698b8fd5c955ca57b8ae118f8333db4a9da55cdfe81b750b614fdf5b4a3e50' 
  AND token = 'JUU3xrdhBW5ReRtxSl5AX2HwdcGXiXQzViZS7t8IhXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}