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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43f1f4d1cff446652bfd2455dc567ab39d4906b132ff1dd2df48c1649827915c' 
  AND token = 'BoRhqpOh+p9cCW+5GCdiO4QPEh6wyJt+rJcEuIKDWa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}