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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '533227a57a864fb8770de46c3e9b59bfc91b834be582cd62784310d6fc47e726' 
  AND token = 'nDLvtYo1lPHWkSd0MGb5WVteic5tsCdf+uEsNSXiwiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}