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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a9f3e3145426391cfb8a531fa411404fdb70fdbd0e130a63383d6f80cb20f8c' 
  AND token = 'UVSDTrRBnKrQieBdYa0tGbcDqUg0k+9tnmQM2GvRHwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}