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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cfb0251a6923530dc08d9f72c25a7a408bd74f72493d7a3e1ec6d012282b8a1' 
  AND token = 'yyGtIuumuOn+A7fpnzYxyijoYQMaSezyd6Y8MHpwu0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}