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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f07a1f28c28d3d5f7b0406f49bad904f4ee0ba477a1ddee91d915c7a063c40c6' 
  AND token = '0Ai6iM6YPhQxgomOJDVRqnrHTV01OqM9QwGXiHJdGkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}