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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f5ecca539457fcdf45374b6527b095a3a071c71ab33fffb8ee715db5f4508cd' 
  AND token = 'EN/TXUXMY2u0rPS7l3RVPwvmh+4EDsbtaXpqJJqfBYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}