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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10b19f246c3afb899b9d56ccf755b5b000fdf876b7ed4229be29abc40e154366' 
  AND token = 'UvqXo0ARZYhig96Pu2/YBfiw/ZZ/EalBXlDniSm0dkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}