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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd117414e52c9a3a98c239a232da46be59c2164e57963e56c26141911358b155' 
  AND token = 'AsuTEHOGczHb1Ozo0X9rkSp5OSuCRVuYnXEInrJr4nA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}