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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c6d98f2fd80947d02fc30beb42a02c85e0145d00315f18b492afcd1f1f534aa' 
  AND token = '8VFx8TWslfOhX8qLnLq95drAYJbYpEoW64HLtKrqg0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}