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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d853d3379df705441180f0e1e66e246ec0f1946d7c2fdc0612ab1fff15c75a3' 
  AND token = 'gUgWt/SrEKEaIF07OWZm44PkVD6I4sdFMK/E0TpPd18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}